Childhood patterns of overweight and wheeze and subsequent risk of current asthma and obesity in adolescence.

ABSTRACT:

Background

Obesity and asthma in childhood often co-occur. Few studies have examined this relationship using repeated measures of body mass index (BMI) or asthma symptoms (such as wheeze).

Objective

We compared two analytic approaches for repeated measures data to investigate this relationship.

Methods

Our baseline sample consisted of 1277 children enrolled in a Boston-area cohort with BMI or wheeze at age 1 year and no missing covariates. We used latent class growth models (LCGM) and inverse probability weighting (IPW) of marginal structural models to examine the extent to which presence of overweight across childhood was associated with early adolescent current asthma, and conversely of repeated measures of wheeze across childhood with early adolescent obesity.

R

SUBMITTER: Aris IM 

PROVIDER: S-EPMC8380670 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature