A GPU-accelerated framework for rapid estimation of scanner-specific scatter in CT for virtual imaging trials.

ABSTRACT: Virtual imaging trials (VITs), defined as the process of conducting clinical imaging trials using computer simulations, offer a time- and cost-effective alternative to traditional imaging trials for CT. The clinical potential of VITs hinges on the realism of simulations modeling the image acquisition process, where the accurate scanner-specific simulation of scatter in a time-feasible manner poses a particular challenge. To meet this need, this study proposes, develops, and validates a rapid scatter estimation framework, based on GPU-accelerated Monte Carlo (MC) simulations and denoising methods, for estimating scatter in single source, dual-source, and photon-counting CT. A CT simulator was developed to incorporate parametric models for an anti-scatter grid and a curved energy integrating

SUBMITTER: Sharma S 

PROVIDER: S-EPMC8381286 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature