Natural history of histologically confirmed high-grade cervical intraepithelial neoplasia during pregnancy: meta-analysis.

ABSTRACT:

Objectives

This study aimed to conduct a meta-analysis of estimates of the natural history of high-grade cervical intraepithelial neoplasia (CIN) during pregnancy.

Setting

Studies examining the clinical courses of histologically confirmed high-grade CIN during pregnancy.

Participants

We searched PubMed, Web of Science and Embase for eligible studies. Studies were included if they reported the data regarding the natural history of histologically confirmed high-grade CIN during pregnancy. Final estimates were from the meta-analysis of 10 eligible studies.

Primary outcome measures

The regression rate, persistence rate and progression rate of histologically proven untreated high-grade CIN during pregnancy.

Results

A total of 10 original studies were included

SUBMITTER: Chen C 

PROVIDER: S-EPMC8381303 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature