Age- and sex-based resource utilisation and costs in patients with acute chest pain undergoing cardiac CT angiography: pooled evidence from ROMICAT II and ACRIN-PA trials.

ABSTRACT:

Objectives

To determine resource utilisation according to age and gender-specific subgroups in two large randomized diagnostic trials.

Methods

We pooled patient-specific data from ACRIN-PA 4005 and ROMICAT II that enrolled subjects with acute chest pain at 14 US sites. Subjects were randomized between a standard work-up and a pathway utilizing cardiac computed tomography angiography (CCTA) and followed for the occurrence of acute coronary syndrome (ACS) and resource utilisation during index hospitalisation and 1-month follow-up. Study endpoints included diagnostic accuracy of CCTA for the detection of ACS as well as resource utilisation.

Results

Among 1240 patients who underwent CCTA, negative predictive value of CCTA to rule out ACS remained very high (≥99.4%). The p

SUBMITTER: Bamberg F 

PROVIDER: S-EPMC8382042 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature