Household Transmission and Clinical Features of SARS-CoV-2 Infections by Age in 2 US Communities.

ABSTRACT: Examine age differences in SARS-CoV-2 transmission risk from primary cases and infection risk among household contacts, and symptoms among those with SARS-CoV-2 infection. People with SARS-CoV-2 infection in Nashville, Tennessee and central and western Wisconsin and their household contacts were followed daily for 14 days to ascertain symptoms and secondary transmission events. Households were enrolled between April 2020 and April 2021. Secondary infection risks (SIR) by age of the primary case and contacts were estimated using generalized estimating equations. The 226 primary cases were followed by 198 (49%) secondary SARS-CoV-2 infections among 404 household contacts. Age group-specific SIR among contacts ranged from 36% to 53%, with no differences by age. SIR was lower from primary case

SUBMITTER: McLean HQ 

PROVIDER: S-EPMC8382134 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature