Plasma Exchange in Patients With Severe Coronavirus Disease 2019: A Single-Center Experience.

ABSTRACT:

Importance

Recent evidence suggests a multilevel inflammatory syndrome as a driving factor in some of the most severely ill coronavirus disease 2019 patients with overlapping features to other hyperinflammatory or autoimmune diseases. Therefore, plasma exchange is considered as potential therapy in these patients.

Objectives

We characterize the longitudinal therapeutic efficacy and safety profile of plasma exchange in critically ill patients with clinical and laboratory evidences of coronavirus disease 2019-related immunopathology.

Design setting and participants

A retropsective case-control study of critically ill coronavirus disease 2019 patients treated with plasma exchange at Heidelberg University Hospital between March and December 2020. Plasma exchange-treated p

SUBMITTER: Nusshag C 

PROVIDER: S-EPMC8382335 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature