Insomnia symptoms and subclinical myocardial injury: Data from the Nord-Trondelag Health (HUNT) study.

ABSTRACT: Insomnia symptoms are associated with increased risk of heart failure (HF) and cardiovascular (CV) mortality. We hypothesised that insomnia symptoms are cross-sectionally associated with increased cardiac troponin I (cTnI), a biomarker of subclinical myocardial injury, and that phenotyping by insomnia symptoms and cTnI enhances longitudinal risk stratification in the general population. In a population-based study, cTnI was measured in 8,398 participants (median age 49 years, 55% women), who had answered questionnaires regarding insomnia symptoms. Association between cTnI and insomnia symptoms was assessed by linear regression analysis for each response category of a sleep questionnaire. Insomnia symptoms were defined as having difficulty falling asleep almost every night, difficulty maint

SUBMITTER: Sigurdardottir FD 

PROVIDER: S-EPMC8382789 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature