Derivation and External Validation of a Risk Index for Predicting Acute Kidney Injury Requiring Kidney Replacement Therapy After Noncardiac Surgery.

ABSTRACT:

Importance

Severe acute kidney injury (AKI) is a serious postoperative complication. A tool for predicting the risk of AKI requiring kidney replacement therapy (KRT) after major noncardiac surgery might assist with patient counseling and targeted use of measures to reduce this risk.

Objective

To derive and validate a predictive model for AKI requiring KRT after major noncardiac surgery.

Design, setting, and participants

In this prognostic study, 5 risk prediction models were derived and internally validated in a population-based cohort of adults without preexisting kidney failure who underwent noncardiac surgery in Alberta, Canada, between January 1, 2004, and December 31, 2013. The best performing model and corresponding risk index were externally validated in a popu

SUBMITTER: Wilson TA 

PROVIDER: S-EPMC8383136 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature