Left Ventricular Diastolic Dysfunction Among Youth with Obesity and History of Elevated Blood Pressure.

ABSTRACT:

Objective

To assess prevalence of and factors associated with left ventricular diastolic dysfunction (LVDD) in youth with obesity and elevated blood pressure (BP).

Study design

This was a cross-sectional analysis of baseline and follow-up visits of 83 youth, 5-21 years, evaluated for overweight/obesity and elevated BP in a multidisciplinary clinic. LVDD was defined according to established adult criteria (LVDD_adult; E/A < 1, E/e' > 14, or e'/a' < 0.8) and pediatric criteria (LVDD_peds; E/A <10th percentile, E/e' >99th percentile, or e'/a' <1st percentile) based on data from 103 age-sex matched healthy controls. Baseline factors associated with LVDD_peds were examined using Wilcoxon rank sum and χ² tests. Multiple logistic regression

SUBMITTER: Abdul-Raheem JN 

PROVIDER: S-EPMC8383194 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature