The severity and risk factors for mortality in immunocompromised adult patients hospitalized with influenza-related pneumonia.

ABSTRACT:

Objective

To explore disease severity and risk factors for 30-day mortality of adult immunocompromised (IC) patients hospitalized with influenza-related pneumonia (Flu-p).

Method

A total of 122 IC and 1191 immunocompetent patients hospitalized with Flu-p from January 2012 to December 2018 were recruited retrospectively from five teaching hospitals in China.

Results

After controlling for confounders, multivariate logistic regression analysis showed that immunosuppression was associated with increased risks for invasive ventilation [odds ratio: (OR) 2.475, 95% confidence interval (CI): 1.511-4.053, p < 0.001], admittance to the intensive care unit (OR: 3.247, 95% CI 2.064-5.106, p < 0.001), and 30-day mortality (OR: 3.206, 95% CI 1.926-5.335, p < 0.001) in patients with

SUBMITTER: Chen L 

PROVIDER: S-EPMC8383249 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature