Efficacy of radiotherapy for gastric bleeding associated with advanced gastric cancer.

ABSTRACT:

Background

Gastric bleeding negatively impacts the quality of life of patients with unresectable advanced gastric cancer and is frequently lethal. We investigated the efficacy of RT for palliation of gastric bleeding from gastric cancer and identified an optimal radiotherapy (RT) strategy.

Methods

The study analyzed 57 patients submitted to palliative RT for gastric bleeding associated with gastric cancer between January 2009 and February 2019. Changes in hemoglobin (Hb) levels were analyzed based on measurements taken before and immediately, 1 month, and 2 months after RT. Re-bleeding after RT was identified as either Hb level dropping to < 7.0 g/dL or the administration of a blood transfusion after RT.

Results

The median biologically effective dose (α/β = 10) was 37

SUBMITTER: Lee J 

PROVIDER: S-EPMC8383356 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature