A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates.

ABSTRACT: In this paper, we outline a method for surgical preparation that allows for the practical planning of a variety of neurosurgeries in NHPs solely using data extracted from magnetic resonance imaging (MRI). This protocol allows for the generation of 3D printed anatomically accurate physical models of the brain and skull, as well as an agarose gel model of the brain modeling some of the mechanical properties of the brain. These models can be extracted from MRI using brain extraction software for the model of the brain, and custom code for the model of the skull. The preparation protocol takes advantage of state-of-the-art 3D printing technology to make interfacing brains, skulls, and molds for gel brain models. The skull and brain models can be used to visualize brain tissue inside the skull

SUBMITTER: Ojemann WKS 

PROVIDER: S-EPMC8384434 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature