Post-Trial Enhanced Deployment and Technical Performance with the MISTIE Procedure per Lessons Learned.

ABSTRACT:

Objective

We hypothesize that procedure deployment rates and technical performance with minimally invasive surgery and thrombolysis for intracerebral hemorrhage (ICH) evacuation (MISTIE) can be enhanced in post-trial clinical practice, per Phase III trial results and lessons learned.

Materials and methods

We identified ICH patients and those who underwent MISTIE procedure between 2017-2021 at a single site, after completed enrollments in the Phase III trial. Deployment rates, complications and technical outcomes were compared to those observed in the trial. Initial and final hematoma volume were compared between site measurements using ABC/2, MISTIE trial reading center utilizing manual segmentation, and a novel Artificial Intelligence (AI) based volume assessment.

Result

SUBMITTER: Mansour A 

PROVIDER: S-EPMC8384714 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature