Biofilm properties in relation to treatment outcome in patients with first-time periprosthetic hip or knee joint infection.

ABSTRACT:

Background

Periprosthetic joint infections (PJI) are challenging complications following arthroplasty. Staphylococci are a frequent cause of PJI and known biofilm producers. Biofilm formation decreases antimicrobial susceptibility, thereby challenging favourable treatment outcomes. The aims of this study were to characterize the biofilm abilities and antimicrobial susceptibilities of staphylococci causing first-time PJI and correlate them to clinical outcome (infection resolution and recurrence).

Methods

Reoperations for PJI of the hip or knee between 1st January 2012 to 30th June 2015 performed at the Sahlgrenska University Hospital were identified in a local database. Medical records were reviewed and clinical parameters recorded for patients whose intraoperative bacterial

SUBMITTER: Svensson Malchau K 

PROVIDER: S-EPMC8385121 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature