Washed Microbiota Transplantation Lowers Blood Pressure in Patients With Hypertension.

ABSTRACT:

Background

Although transplantation of the fecal microbiota from normotensive donors has been shown to have an antihypertensive effect in hypertensive animal models, its effect on blood pressure in patients with hypertension is unclear. This study aimed to assess the effect of washed microbiota transplantation (WMT) from normotensive donors on blood pressure regulation in hypertensive patients.

Methods

The clinical data of consecutive patients treated with washed microbiota transplantation (WMT) were collected retrospectively. The blood pressures of hypertensive patients before and after WMT were compared. The factors influencing the antihypertensive effect of WMT in hypertensive patients and fecal microbial composition of donors and hypertensive patients were also analyzed.

SUBMITTER: Zhong HJ 

PROVIDER: S-EPMC8385408 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature