Anaerobic Growth of Listeria monocytogenes on Rhamnose Is Stimulated by Vitamin B₁₂ and Bacterial Microcompartment-Dependent 1,2-Propanediol Utilization.

ABSTRACT: The foodborne pathogen Listeria monocytogenes can form proteinaceous organelles called bacterial microcompartments (BMCs) that optimize the utilization of substrates, such as 1,2-propanediol, and confer an anaerobic growth advantage. Rhamnose is a deoxyhexose sugar abundant in a range of environments, including the human intestine, and can be degraded in anaerobic conditions into 1,2-propanediol, next to acetate and lactate. Rhamnose-derived 1,2-propanediol was found to link with BMCs in some human pathogens such as Salmonella enterica, but the involvement of BMCs in rhamnose metabolism and potential physiological effects on L. monocytogenes are still unknown. In this study, we first test the effect of rhamnose uptake and utilization on anaerobic growth of L. monocytogenes EGDe without or

SUBMITTER: Zeng Z 

PROVIDER: S-EPMC8386454 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature