Overlapping of Independent SARS-CoV-2 Nosocomial Transmissions in a Complex Outbreak.

ABSTRACT: SARS-CoV-2 nosocomial outbreaks in the first COVID-19 wave were likely associated with a shortage of personal protective equipment and scarce indications on control measures. Having covered these limitations, updates on current SARS-CoV-2 nosocomial outbreaks are required. We carried out an in-depth analysis of a 27-day nosocomial outbreak in a gastroenterology ward in our hospital, potentially involving 15 patients and 3 health care workers. Patients had stayed in one of three neighboring rooms in the ward. The severity of the infections in six of the cases and a high fatality rate made the clinicians suspect the possible involvement of a single virulent strain persisting in those rooms. Whole-genome sequencing (WGS) of the strains from 12 patients and 1 health care worker revealed an une

SUBMITTER: Perez-Lago L 

PROVIDER: S-EPMC8386460 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature