Ontology highlight
ABSTRACT:
SUBMITTER: Mustafa M
PROVIDER: S-EPMC8386514 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Mustafa Muhamad M Abd El-Hafeez Amer Ali AA Abdelhafeez Dalia A DA Abdelhamid Dalia D Mostafa Yaser A YA Ghosh Pradipta P Hayallah Alaa M AM A Abuo-Rahma Gamal El-Din GE
Future medicinal chemistry 20210803 18
FAK, a nonreceptor tyrosine kinase, has been recognized as a novel target class for the development of targeted anticancer agents. Overexpression of FAK is a common occurrence in several solid tumors, in which the kinase has been implicated in promoting metastases. Consequently, designing and developing potent FAK inhibitors is becoming an attractive goal, and FAK inhibitors are being recognized as a promising tool in our armamentarium for treating diverse cancers. This review comprehensively su ...[more]