Repeated talaporfin sodium photodynamic therapy for esophageal cancer: safety and efficacy.

ABSTRACT:

Background

Talaporfin sodium photodynamic therapy (tPDT) is an effective salvage treatment for local failure after chemoradiotherapy for esophageal cancer. Repeated tPDT could also be indicated for local recurrence or residue after the first salvage tPDT. However, the safety and efficacy of repeated tPDT have not been elucidated.

Methods

We reviewed 52 patients with esophageal cancer who were treated with the first tPDT at Kyoto University Hospital between October 2015 and April 2020.

Results

Among 52 patients, repeated tPDT after the first tPDT was indicated for 13 patients (25%), of which six had residual tumor, four had local recurrence after complete response (CR) after the first tPDT at the primary site, and six had metachronous lesion. The total session of repea

SUBMITTER: Tamaoki M 

PROVIDER: S-EPMC8387249 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature