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In community-dwelling women frailty is associated with imminent risk of osteoporotic fractures.


ABSTRACT: Frailty reflects an accelerated health decline. Frailty is a consequence of fracture and contributes to fracture. Greater frailty was associated with higher fracture risk. Frail women were at immediate risk (within 24 months) of a hip or major fracture. Fracture prevention could be improved by considering frailty status.

Introduction

Frailty encompasses the functional decline in multiple systems, particularly the musculoskeletal system. Frailty can be a consequence of and contribute to fracture, leading to a cycle of further fractures and greater frailty. This study investigates this association, specifically time frames for risk, associated fracture types, and how grade of frailty affects risk.

Methods

The study is performed in the OPRA cohort of 1044, 75-year-old women. A f

SUBMITTER: Bartosch P 

PROVIDER: S-EPMC8387253 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature