Low-dose aspirin confers a survival benefit in patients with pathological advanced-stage oral squamous cell carcinoma.

ABSTRACT: Oral squamous cell carcinoma (OSCC) remains one of the most challenging clinical problems in the field due to its high rate of locoregional and distant metastases. However, studies that assess the association between aspirin use and survival in patients with OSCC are limited. Moreover, patients that recruited from those studies might have tumors that arose from different anatomic regions of the head and neck, including the oral cavity, oropharynx, etc. Since tumors within these distinct anatomic regions are unique in the context of epidemiology and tumor progression, we sought to evaluate the association of aspirin use with squamous cell carcinomas located within the oral cavity only. In this 10-year cohort study, we evaluated aspirin use and survival rates in relation to clinical characte

SUBMITTER: Luo SD 

PROVIDER: S-EPMC8387371 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature