Ontology highlight
ABSTRACT:
SUBMITTER: Meyer SN
PROVIDER: S-EPMC8387591 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Meyer Stefanie N SN Koul Sanjay S Pasqualucci Laura L
Frontiers in immunology 20210812
Over the last decades, the revolution in DNA sequencing has changed the way we understand the genetics and biology of B-cell lymphomas by uncovering a large number of recurrently mutated genes, whose aberrant function is likely to play an important role in the initiation and/or maintenance of these cancers. Dissecting how the involved genes contribute to the physiology and pathology of germinal center (GC) B cells -the origin of most B-cell lymphomas- will be key to advance our ability to diagno ...[more]