Genomic analysis of the carboxylesterase family in the salmon louse (Lepeophtheirus salmonis).

ABSTRACT: The pyrethroid deltamethrin and the macrocyclic lactone emamectin benzoate (EMB) are used to treat infestations of farmed salmon by parasitic salmon lice, Lepeophtheirus salmonis. While the efficacy of both compounds against Atlantic populations of the parasite has decreased as a result of the evolution of resistance, the molecular mechanisms of drug resistance in L. salmonis are currently not fully understood. The functionally diverse carboxylesterases (CaE) family includes members involved in pesticide resistance phenotypes of terrestrial arthropods. The present study had the objective to characterize the CaE family in L. salmonis and assess its role in drug resistance. L. salmonis CaE homologues were identified by homology searches in the parasite's transcriptome and genome. The transcr

SUBMITTER: Tschesche C 

PROVIDER: S-EPMC8387733 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature