Helicobacter pylori Eradication Therapy Affect the Gut Microbiota and Ghrelin Levels.

ABSTRACT: Background: Antibiotic therapy used to eradicate Helicobacter pylori has been associated with changes in plasma ghrelin and alterations in the gut microbiota. On the other hand, changes in ghrelin levels have been related to changes in gut microbiota composition. Our aim was to evaluate the relationship between changes in the gut microbiota and ghrelin levels in H. pylori infected patients who received antibiotic treatment for its eradication. Methods: A prospective case-control study that included forty H. pylori-positive patients who received eradication therapy (omeprazole, clarithromycin, and amoxicillin) and twenty healthy H. pylori antigen-negative participants. Patients were evaluated, including clinical, anthropometric and dietary variables

SUBMITTER: Martin-Nunez GM 

PROVIDER: S-EPMC8387937 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature