Evaluation of Pharmacologic Treatments for H1 Antihistamine-Refractory Chronic Spontaneous Urticaria: A Systematic Review and Network Meta-analysis.

ABSTRACT:

Importance

The comparative benefits and harms of all available treatments for H1 antihistamine-refractory chronic spontaneous urticaria (CSU) have not been established.

Objective

To evaluate different treatment effects of pharmacologic treatments among patients with H1 antihistamine-refractory CSU.

Data sources

Searches were conducted of MEDLINE, Embase, PubMed, Cochrane Library, Web of Science, Scopus, and CINAHL from inception to April 19, 2021, with no language restrictions. Gray literature from Google Scholar, ongoing trial registers, and preprint reports was added to the searches of electronic databases.

Study selection

Randomized clinical trials using validated measurement tools that investigated the benefits and harms of pharmacologic treatments among ad

SUBMITTER: Nochaiwong S 

PROVIDER: S-EPMC8387945 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature