Should colorectal cancer screening start at different ages for men and women? Cost-effectiveness analysis for a resource-constrained service.

ABSTRACT:

Background

Men have a greater risk of colorectal cancer (CRC) than women, but population screening currently starts at the same age for both sexes.

Aim

This analysis investigates whether, in a resource-constrained setting, it would be more effective and cost-effective for men and women to start screening for CRC at different ages.

Methods and results

An economic modeling analysis was carried out using the Microsimulation Model in Cancer of the Bowel to compare sex-stratification against screening everyone from the same age, taking an English National Health Service perspective. Screening men from age 56 and women from age 60, rather than screening everyone from age 58 using a Fecal Immunochemical Test (FIT) threshold of 120 μg/g is expected to produce an additional 0.

SUBMITTER: Thomas C 

PROVIDER: S-EPMC8388164 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature