Correlation between perioperative parecoxib use and postoperative acute kidney injury in patients undergoing non-cardiac surgery: a retrospective cohort analysis.

ABSTRACT:

Objective

The association of non-steroidal anti-inflammatory drugs with postoperative acute kidney injury (AKI) is controversial. However, there are few studies focusing on the association between parecoxib and postoperative AKI. Our study aimed at the possible correlation between the intraoperative administration of cyclooxygenase-2 inhibitors parecoxib and perioperative AKI.

Design

A retrospective cohort study.

Setting

Third Xiangya Hospital of Central South University in Hunan Province, China.

Participants

The electronic medical records and laboratory results were obtained from 9246 adult patients (18-60 years) undergoing non-cardiac surgery performed between 1 January 2012 and 31 August 2017. Study groups were treated with or without parecoxib.

Intervent

SUBMITTER: Tang YZ 

PROVIDER: S-EPMC8388276 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature