Innate and Adaptive Immune Assessment at Admission to Predict Clinical Outcome in COVID-19 Patients.

ABSTRACT: During the COVID-19 pandemic, many studies have been carried out to evaluate different immune system components to search for prognostic biomarkers of the disease. A broad multiparametric antibody panel of cellular and humoral components of the innate and the adaptative immune response in patients with active SARS-CoV-2 infection has been evaluated in this study. A total of 155 patients were studied at admission into our center and were categorized according to the requirement of oxygen therapy as mild or severe (the latter being those with the requirement). The patients with severe disease were older and had high ferritin, D-dimer, C-reactive protein, troponin, interleukin-6 (IL-6) levels, and neutrophilia with lymphopenia at admission. Moreover, the patients with mild symptoms had signif

SUBMITTER: San Segundo D 

PROVIDER: S-EPMC8389676 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature