Convalescent plasma is of limited clinical benefit in critically ill patients with coronavirus disease-2019: a cohort study.

ABSTRACT:

Background

Recently, convalescent plasma (CP) transfusion was employed for severe or critically ill patients with coronavirus disease-2019. However, the benefits of CP for patients with different conditions are still in debate. To contribute clinical evidence of CP on critically ill patients, we analyze the characteristics and outcomes of patients with or without CP transfusion.

Methods

In this cohort study, 14 patients received CP transfusion based on the standard treatments, whereas the other 10 patients received standard treatments as control. Clinical characteristics and outcomes were analyzed. The cumulative survival rate was calculated by Kaplan-Meier survival analysis.

Results

Data analysis was performed on 24 patients (male/female: 15/9) with a median age of 6

SUBMITTER: Huang L 

PROVIDER: S-EPMC8390032 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature