Comprehensive analysis of coagulation indices for predicting survival in patients with biliary tract cancer.

ABSTRACT:

Background

Abnormal activation of the coagulation system has been reported in patients with malignancies, but its prognostic significance in biliary tract cancer (BTC) remains unclear. This study aims to analyze and compare the prognostic value of coagulation indices in patients with BTC.

Methods

The medical records of 450 patients with BTC who underwent surgical resection at our hospital between 2003 and 2017 were retrospectively analyzed. Time-dependent receiver operating characteristic curves were plotted to compare the predictive accuracy of coagulation indices. A predictive nomogram for overall survival (OS) was established based on the Cox regression analysis and validated in both the training and validation cohorts. A novel stratification model was created according t

SUBMITTER: Ke X 

PROVIDER: S-EPMC8390227 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature