Capture of carbon dioxide and hydrogen by engineered Escherichia coli: hydrogen-dependent CO₂ reduction to formate.

ABSTRACT: In times of global climate change and the fear of dwindling resources, we are facing different considerable challenges such as the replacement of fossil fuel-based energy carriers with the coincident maintenance of the increasing energy supply of our growing world population. Therefore, CO₂ capturing and H₂ storing solutions are urgently needed. In this study, we demonstrate the production of a functional and biotechnological interesting enzyme complex from acetogenic bacteria, the hydrogen-dependent CO₂ reductase (HDCR), in the well-known model organism Escherichia coli. We identified the metabolic bottlenecks of the host organisms for the production of the HDCR enzyme complex. Here we show that the recombinant expression of a heterologous enzyme complex t

SUBMITTER: Leo F 

PROVIDER: S-EPMC8390402 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature