Predicting Non-Alcoholic Fatty Liver Disease for Adults Using Practical Clinical Measures: Evidence from the Multi-ethnic Study of Atherosclerosis.

ABSTRACT:

Background

Many adults have risk factors for non-alcoholic fatty liver disease (NAFLD). Screening all adults with risk factors for NAFLD using imaging is not feasible.

Objective

To develop a practical scoring tool for predicting NAFLD using participant demographics, medical history, anthropometrics, and lab values.

Design

Cross-sectional.

Participants

Data came from 6194 white, African American, Hispanic, and Chinese American participants from the Multi-Ethnic Study of Atherosclerosis cohort, ages 45-85 years.

Main measures

NAFLD was identified by liver computed tomography (≤ 40 Hounsfield units indicating > 30% hepatic steatosis) and data on 14 predictors was assessed for predicting NAFLD. Random forest variable importance was used to identify the minim

SUBMITTER: Rodriguez LA 

PROVIDER: S-EPMC8390627 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature