Mouth Washing Impaired SARS-CoV-2 Detection in Saliva.

ABSTRACT:

Background

A previous study demonstrated the performance of the Salivette^® (SARSTEDT, Numbrecht, Germany) as a homogeneous saliva collection system to diagnose COVID-19 by RT-qPCR, notably for symptomatic and asymptomatic patients. However, for convalescent patients, the corroboration of molecular detection of SARS-CoV-2 in paired nasopharyngeal swabs (NPS) and saliva samples was unsatisfactory.

Objectives

The aim of the present work was to assess the concordance level of SARS-CoV-2 detection between paired sampling of NPSs and saliva collected with Salivette^® at two time points, with ten days of interval.

Results

A total of 319 paired samples from 145 outpatients (OP) and 51 healthcare workers (HW) were collected. Unfortunately, at day ten, 73 i

SUBMITTER: Costa MM 

PROVIDER: S-EPMC8391436 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature