Ontology highlight
ABSTRACT:
SUBMITTER: Idda ML
PROVIDER: S-EPMC8393247 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Idda Maria Laura ML Campesi Ilaria I Fiorito Giovanni G Vecchietti Andrea A Urru Silvana Anna Maria SAM Solinas Maria Giuliana MG Franconi Flavia F Floris Matteo M
Biomolecules 20210813 8
Individual response to drugs is highly variable and largely influenced by genetic variants and gene-expression profiles. In addition, it has been shown that response to drugs is strongly sex-dependent, both in terms of efficacy and toxicity. To expand current knowledge on sex differences in the expression of genes relevant for drug response, we generated a catalogue of differentially expressed human transcripts encoded by 289 genes in 41 human tissues from 838 adult individuals of the Genotype-T ...[more]