Conserved Sequence Analysis of Influenza A Virus HA Segment and Its Application in Rapid Typing.
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ABSTRACT:
SUBMITTER: Lin Q
PROVIDER: S-EPMC8393347 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Publications
Conserved Sequence Analysis of Influenza A Virus HA Segment and Its Application in Rapid Typing.
Lin Qianyu Q Ji Xiang X Wu Feng F Ma Lan L
Diagnostics (Basel, Switzerland) 20210723 8
The high mutation rate of the influenza A virus hemagglutinin segment poses great challenges to its long-term effective testing and subtyping. Our conserved sequence searching method achieves high-specificity conserved sequences on H1-H9 subtypes. In addition, PCR experiments show that primers based on conserved sequences can be used in influenza A virus HA subtyping. Conserved sequence-based primers are expected to be long-term, effective subtyping tools for influenza A virus HA. ...[more]
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