Nonalcoholic fatty liver disease and the risk of insulin-requiring gestational diabetes.

ABSTRACT:

Background

Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases; however, there has been little research into its impact on gestational diabetes mellitus (GDM).

Methods

This study included 308,095 women registered in the Korean National Health Insurance Service database, who delivered between 2011 and 2015 and received a health examination within 52 weeks before pregnancy. Insulin-requiring GDM was defined as no insurance claims for diabetes mellitus and a fasting blood glucose level of < 126 mg/dL before pregnancy, and initiation of insulin treatment during pregnancy. A fatty liver index (FLI) was calculated using body mass index, waist circumference, and blood triglyceride and γ-glutamyl transferase levels. FLI scores < 30 ruled out hep

SUBMITTER: You SY 

PROVIDER: S-EPMC8393465 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature