CBmeter study: protocol for assessing the predictive value of peripheral chemoreceptor overactivation for metabolic diseases.

ABSTRACT:

Introduction

Early screening of metabolic diseases is crucial since continued undiagnostic places an ever-increasing burden on healthcare systems. Recent studies suggest a link between overactivated carotid bodies (CB) and the genesis of type 2 diabetes mellitus. The non-invasive assessment of CB activity by measuring ventilatory, cardiac and metabolic responses to challenge tests may have predictive value for metabolic diseases; however, there are no commercially available devices that assess CB activity. The findings of the CBmeter study will clarify the role of the CBs in the genesis of-metabolic diseases and guide the development of new therapeutic approaches for early intervention in metabolic disturbances. Results may also contribute to patient classification and stratificati

SUBMITTER: Lages M 

PROVIDER: S-EPMC8395299 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature