Impedance planimetry values for predicting clinical response following peroral endoscopic myotomy.

ABSTRACT:

Background

There is growing interest in developing impedance planimetry as a tool to enhance the clinical outcomes for endoscopic and surgical management of achalasia. The primary aim of this study was to determine whether impedance planimetry measurements can predict clinical response and reflux following peroral endoscopic myotomy (POEM).

Methods

A multicenter cohort study of patients with achalasia undergoing POEM was established from prospective databases and retrospective chart reviews. Patients who underwent impedance planimetry before and after POEM were included. Clinical response was defined as an Eckardt score of ≤ 3. Tenfold cross-validated area under curve (AUC) values were established for the different impedance planimetry measurements associated with clinical r

SUBMITTER: Moran RA 

PROVIDER: S-EPMC8395534 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature