Microstructured Hyaluronic Acid Hydrogel for Tooth Germ Bioengineering.

ABSTRACT: Tooth loss has been found to adversely affect not just masticatory and speech functions, but also psychological health and quality of life. Currently, teeth replacement options include dentures, bridges, and implants. However, these artificial replacement options remain inferior to biological replacements due to their reduced efficiency, the need for replacements, and the risk of immunological rejection. To this end, there has been a heightened interest in the bioengineering of teeth in recent years. While there have been reports of successfully regenerated teeth, controlling the size and shape of bioengineered teeth remains a challenge. In this study, methacrylated hyaluronic acid (MeHA) was synthesized and microstructured in a hydrogel microwell array using soft lithography. The resultin

SUBMITTER: Park S 

PROVIDER: S-EPMC8395742 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature