Intraoperative vasopressors in head and neck free flap reconstruction.

ABSTRACT:

Introduction

Historically, there were concerns vasopressors impair free flap outcomes, but recent studies suggest vasopressors are safe. Here we investigate this controversy by (1) evaluating vasopressors' effect on head and neck free-flap survival and surgical complications, and (2) performing soft tissue and bony subset analysis.

Patients and methods

Post hoc analysis was performed of a single-blinded, prospective, randomized clinical trial at a tertiary care academic medical center involving patients ≥18 years old undergoing head and neck free flap reconstruction over a 16-month period. Patients were excluded if factors prevented accurate FloTrac™ use. Patients were randomized to traditional volume-based support, or goal-directed support including vasopressor use. Primary

SUBMITTER: Taylor RJ 

PROVIDER: S-EPMC8396078 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature