Electrochemical Skin Conductance Alterations during Spinal Cord Stimulation: An Experimental Study.

ABSTRACT: Despite the well-known clinical effects of spinal cord stimulation (SCS), the mechanisms of action have not yet been fully unraveled. The primary aim of this study was to measure whether electrochemical skin conductance, as a measure of peripheral sympathetic autonomic function, is altered by SCS. A second aim was to compare skin conductance levels of patients with failed back surgery syndrome (FBSS) with age- and sex-matched healthy controls. Twenty-three patients with FBSS treated with SCS participated in this study. Sudomotor function was measured with the Sudoscan^TM instrument on the hands and feet during SCS on and off states. Difference scores in skin conductance between patients and age- and sex-matched healthy controls were calculated. Normal sudomotor function at the pa

SUBMITTER: Goudman L 

PROVIDER: S-EPMC8397194 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature