Association between radicular low back pain and constipation: a retrospective cohort study using a real-world national database.

ABSTRACT:

Introduction

Previous observational studies have reported an association between lumbosacral radiculopathy (LSR), a form of low back pain (LBP) with nerve root involvement, and constipation. However, it is unclear whether this association is due to confounding variables such as comorbidities and medications.

Objectives

This study explores the possible association between LSR and constipation, with the hypothesis that adults with LSR have increased odds of developing constipation compared with those with nonradicular LBP.

Methods

Adults aged 18 to 49 years with incident LSR and nonradicular LBP were identified from a national 70 million patient electronic health records network (TriNetX). Propensity score matching (PSM) was used to control for covariates and determine

SUBMITTER: Trager RJ 

PROVIDER: S-EPMC8397289 | biostudies-literature | 2021 Sep-Oct

REPOSITORIES: biostudies-literature