Human osteoblast and fibroblast response to oral implant biomaterials functionalized with non-thermal oxygen plasma.

ABSTRACT: Plasma-treatment of oral implant biomaterials prior to clinical insertion is envisaged as a potential surface modification method for enhanced implant healing. To investigate a putative effect of plasma-functionalized implant biomaterials on oral tissue cells, this investigation examined the response of alveolar bone osteoblasts and gingival fibroblasts to clinically established zirconia- and titanium-based implant surfaces for bone and soft tissue integration. The biomaterials were either functionalized with oxygen-plasma in a plasma-cleaner or left untreated as controls, and were characterized in terms of topography and wettability. For the biological evaluation, the cell adhesion, morphogenesis, metabolic activity and proliferation were examined, since these parameters are closely inter

SUBMITTER: Rabel K 

PROVIDER: S-EPMC8397744 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature