Application of an automatic segmentation method for evaluating cardiac structure doses received by breast radiotherapy patients.

ABSTRACT:

Background and purpose

Quantifying radiation dose to cardiac substructures is important for research on the etiology and prevention of complications following radiotherapy; however, segmentation of substructures is challenging. In this study we demonstrate the application of our atlas-based automatic segmentation method to breast cancer radiotherapy plans for generating radiation doses in support of late effects research.

Material and methods

We applied our segmentation method to contour heart substructures on the computed tomography (CT) images of 70 breast cancer patients who received external photon radiotherapy. Two cardiologists provided manual segmentation of the whole heart (WH), left/right atria, left/right ventricles, and left anterior descending artery (LAD). The a

SUBMITTER: Jung JW 

PROVIDER: S-EPMC8397890 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature