Solvatomorphism of Moxidectin.

ABSTRACT: The solvatomorphism of the anthelmintic drug moxidectin is investigated, and a new solvatomorph with nitromethane is reported. Moreover, the hitherto unknown crystal structures of the solvatomorphs with ethanol and 2-propanol are reported and discussed. The thermal characterization of these solvatomorphs through variable-temperature powder X-ray diffraction analysis (VT-PXRD) is also described, providing new insights into the crystallochemistry of this active pharmaceutical ingredient.

SUBMITTER: Grell T 

PROVIDER: S-EPMC8398095 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature