Ontology highlight
ABSTRACT:
SUBMITTER: Tolomeo AM
PROVIDER: S-EPMC8399368 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Tolomeo Anna Maria AM Quarta Santina S Biasiolo Alessandra A Ruvoletto Mariagrazia M Pozzobon Michela M De Lazzari Giada G Malvicini Ricardo R Turato Cristian C Arrigoni Giorgio G Pontisso Patrizia P Muraca Maurizio M
Pharmaceuticals (Basel, Switzerland) 20210721 8
Extracellular vesicles (EVs) are increasingly studied as vectors for drug delivery because they can transfer a variety of molecules across biological barriers. SerpinB3 is a serine protease inhibitor that has shown a protective anti-apoptotic function in a variety of stressful conditions. The aim of this study was to evaluate protection from oxidative stress-induced damage, using extracellular vesicles that overexpress SerpinB3 (EVs-SB3) in order to enhance the effect of extracellular vesicles o ...[more]