Egg Case Protein 3: A Constituent of Black Widow Spider Tubuliform Silk.

ABSTRACT: Spider silk has outstanding mechanical properties, rivaling some of the best materials on the planet. Biochemical analyses of tubuliform silk have led to the identification of TuSp1, egg case protein 1, and egg case protein 2. TuSp1 belongs to the spidroin superfamily, containing a non-repetitive N- and C-terminal domain and internal block repeats. ECP1 and ECP2, which lack internal block repeats and sequence similarities to the highly conserved N- and C-terminal domains of spidroins, have cysteine-rich N-terminal domains. In this study, we performed an in-depth proteomic analysis of tubuliform glands, spinning dope, and egg sacs, which led to the identification of a novel molecular constituent of black widow tubuliform silk, referred to as egg case prote

SUBMITTER: Shanafelt M 

PROVIDER: S-EPMC8399404 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature