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Early Post-Transplant Leptin Concentration Changes in Kidney Transplant Recipients.


ABSTRACT: Background and Objectives: Kidney transplant recipients represent a unique population with metabolic abnormalities, altered nutritional and immune status, as well as an imbalanced regulation of adipocytokine metabolism. Leptin is a hormonally active protein mainly produced by fat tissue that modulates appetite, satiety, and influences growth, energy, and bone metabolism. There has been great interest in the role of this hormone in chronic kidney disease-related protein energy wasting; thus, a positive leptin correlation with body mass index and fat mass was confirmed. This study was designed to determine the association of pre and post-kidney transplant leptin concentration with nutritional status and body composition. Materials and Methods: We studied 65 kidney transplant re

SUBMITTER: Sukackiene D 

PROVIDER: S-EPMC8399685 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature