A Fast and Convenient Synthesis of New Water-Soluble, Polyanionic Dendrimers.

ABSTRACT: Reasonably simple, efficient, and possessing aspects of generality, the methodology for the synthesis of new, water-soluble, dendrimeric polyesters with great potential applications as antiviral drugs in their own right is described. The essential aspect of the presented approach is a quite unique, immediate access to the polyanionic material at each generation during divergent synthesis. Six target polyanionic dendrimers (generations 1, 2, and 3) have been synthesized. The key monomers applied in this project were 1,3,5-benzenetricarboxylic acid derivatives, which also worked as direct precursors of the charged dendrimer surface.

SUBMITTER: Salamonczyk GM 

PROVIDER: S-EPMC8399870 | biostudies-literature |

REPOSITORIES: biostudies-literature