Infants' First Solid Foods: Impact on Gut Microbiota Development in Two Intercontinental Cohorts.

ABSTRACT: The introduction of solid foods is an important dietary event during infancy that causes profound shifts in the gut microbial composition towards a more adult-like state. Infant gut bacterial dynamics, especially in relation to nutritional intake remain understudied. Over 2 weeks surrounding the time of solid food introduction, the day-to-day dynamics in the gut microbiomes of 24 healthy, full-term infants from the Baby, Food & Mi and LucKi-Gut cohort studies were investigated in relation to their dietary intake. Microbial richness (observed species) and diversity (Shannon index) increased over time and were positively associated with dietary diversity. Microbial community structure (Bray-Curtis dissimilarity) was determined predominantly by individual and age (days). The extent of change

SUBMITTER: Homann CM 

PROVIDER: S-EPMC8400337 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature